The paper entitled "Poly(2-Hydroxyethyl Methacrylate) Hydrogel-Based Microneedles for Bioactive Release" has been published in Bioengineering.  The minimally invasive pHEMA hydrogel microneedles release bioactives like estradiol, melatonin, and meropenem, demonstrating strong mechanical properties for tissue penetration. The study highlights their potential in treating diverse medical conditions.